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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 4.55
Human Site: S163 Identified Species: 6.25
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S163 I V G F F D D S F S E A H S E
Chimpanzee Pan troglodytes XP_001159528 485 54945 S143 I V G F F D D S F S E A H S E
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 L138 V V G F F D D L F S E A H S E
Dog Lupus familis XP_535453 687 75990 L345 V V G F F Q D L F S E A H S E
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 L163 V V G F F R D L F S D G H S E
Rat Rattus norvegicus P11598 505 56605 L163 V V G F F R D L F S D G H S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 L140 V V G F F K D L F S E A H S E
Chicken Gallus gallus Q8JG64 505 56163 A161 V V G F F R D A S G D A Y S E
Frog Xenopus laevis NP_001080051 502 56103 L159 V V G F F R D L Y S G P H S E
Zebra Danio Brachydanio rerio NP_998070 488 54656 E155 V V G F F S G E D S A Q L A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 E165 I G F F K D L E S E E A K T F
Honey Bee Apis mellifera XP_623282 490 55838 E160 V V G F F E K E D L S L A T T
Nematode Worm Caenorhab. elegans P34329 618 69779 D285 I G F F A T E D S T A F E A F
Sea Urchin Strong. purpuratus XP_782981 472 51996 E154 I V G F F A D E T S A G L K E
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 F175 I V G I F A E F S G T E F T N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 L170 A V G V F P K L S G D E F D S
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 K168 P V I V Q S G K I D A D F N A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 86.6 80 N.A. 66.6 66.6 N.A. 80 53.3 60 40 N.A. 33.3 26.6 13.3 53.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 80 80 N.A. 86.6 80 73.3 53.3 N.A. 40 46.6 33.3 53.3
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 26.6 N.A. 20 6.6 N.A.
P-Site Similarity: N.A. 40 N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 6 12 0 6 0 0 24 42 6 12 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 24 59 6 12 6 24 6 0 6 0 % D
% Glu: 0 0 0 0 0 6 12 24 0 6 36 12 6 0 65 % E
% Phe: 0 0 12 83 83 0 0 6 42 0 0 6 18 0 12 % F
% Gly: 0 12 83 0 0 0 12 0 0 18 6 18 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 48 0 0 % H
% Ile: 36 0 6 6 0 0 0 0 6 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 6 6 12 6 0 0 0 0 6 6 0 % K
% Leu: 0 0 0 0 0 0 6 42 0 6 0 6 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 % N
% Pro: 6 0 0 0 0 6 0 0 0 0 0 6 0 0 0 % P
% Gln: 0 0 0 0 6 6 0 0 0 0 0 6 0 0 0 % Q
% Arg: 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 12 0 12 30 59 6 0 0 53 6 % S
% Thr: 0 0 0 0 0 6 0 0 6 6 6 0 0 18 6 % T
% Val: 53 89 0 12 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 6 0 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _